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Número total de libros encontrados: 18 para tu búsqueda. Disfruta de tu lectura!!!

Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

Autor: Andrew A. Udy , Jason A. Roberts , Jeffrey Lipman

Número de Páginas: 279

This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

Applications of Pharmacokinetic Principles in Drug Development

Autor: Rajesh Krishna

Número de Páginas: 556

This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling...

Pharmacology

Autor: Miles Hacker , William S. Messer , Kenneth A. Bachmann

Número de Páginas: 607

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students...

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Autor: Nader Rifai

Número de Páginas: 4785

The Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th Edition provides the most current and authoritative guidance on selecting, performing, and evaluating the results of new and established laboratory tests. This classic clinical chemistry reference offers encyclopedic coverage detailing everything you need to know, including: analytical criteria for the medical usefulness of laboratory tests, variables that affect tests and results, laboratory medicine, applications of statistical methods, and most importantly clinical utility and interpretation of laboratory tests. It is THE definitive reference in clinical chemistry and molecular diagnostics, now fully searchable and with quarterly content updates, podcasts, clinical cases, animations, and extended content online through Expert Consult. - Analytical criteria focus on the medical usefulness of laboratory procedures. - Reference ranges show new approaches for establishing these ranges — and provide the latest information on this topic. - Lab management and costs gives students and chemists the practical information they need to assess costs, allowing them to do their job more efficiently and effectively. -...

Neuropsychopharmacology

Autor: Jahangir Moini , Anthony Logalbo , Jennifer G. Schnellmann

Número de Páginas: 600

Neuropsychopharmacology reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary. Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities. - Describes pharmacology principles pertaining to the central and autonomic nervous system - Identifies pharmacological interventions for psychiatric disorders including current evidence-based interventions for depression, schizophrenia...

Pharmaceutical Biotechnology

Autor: Daan J. A. Crommelin , Robert D. Sindelar , Bernd Meibohm

Número de Páginas: 551

This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.

Velázquez. Farmacología Básica y Clínica

Autor: Pedro Lorenzo Fernández

Número de Páginas: 1404

El libro posee un sitio web complementario dónde destacan las herramientas de búsqueda, autoevaluación y estudio que acompañan a la presente edición, con un banco de preguntas conceptuales y de autoevaluación y de imágenes útiles para los estudiantes, docentes, médicos y organismos sanitarios relacionados al área de la salud.

Tietz Textbook of Laboratory Medicine - E-Book

Autor: Nader Rifai

Número de Páginas: 4232

Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. - Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. - Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. - Expert, internationally recognized chapter authors...

Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics

Autor: Amit Kumar Nayak , Kalyan Kumar Sen

Número de Páginas: 488

Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics. In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence. - Provides extensive details on the most recent developments in biopharmaceutics - Contains contributions from leading experts from academia, research, industry and regulatory agencies - Includes high quality illustrations, flow charts and tables for easier understanding of the concepts - Discusses...

Casarett & Doull's Toxicology: The Basic Science of Poisons, 9th Edition

Autor: Curtis D. Klaassen

Número de Páginas: 1639

Toxicology’s gold-standard text - completely updated to reflect the latest breakthroughs and discoveries A Doody’s Core Title for 2024 & 2021! Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere. Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition is logically divided into seven sections: General Principles of Toxicology Disposition of Toxicants Non-Organ Directed Toxicity Target Organ Toxicity Toxic Agents Environmental Toxicology Applications of Toxicology Many new contributors capture the progress made in toxicology over the past few years: This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous...

Textbook of Internal Medicine

Autor: William N. Kelley

Número de Páginas: 1288

This volume emphasizes practicality and now includes features designed to provide authoritative answers to the questions and problems faced by students and practitioners every day. Each section includes a series of Approach to Patients chapters focusing on evaluation and work-up. Also included are complete descriptions of disease-specific entities, with Indications for Referrals and Indications for Hospitalization highlighted for quick reference. There is also a Rapid Access Guide at the front of the book summarizing key facts pertaining to the most important disease entities or clinical problems.

The Cumulative Book Index

Número de Páginas: 2852

A world list of books in the English language.

Pharmacology

Autor: Joyce Lefever Kee , Evelyn R. Hayes

Número de Páginas: 1066

Fully revised and updated, this clinical pharmacology textbook presents pharmacologic principles in a readily accessible format. It combines pharmacology, drug calculation, and administration for adult and pediatric patients into one comprehensive resource. Drugs are presented in a prototype chart format, providing quick access to generic and brand names, dosages, uses, and considerations, as well as the nursing process in drug therapy. Nearly 100 updated drug charts list dosages, indications, contraindications, drug-lab-food interactions, pharmacokinetics, pharmacodynamics, therapeutic effects, side effects, and adverse reactions. (Includes a FREE SIMON website at:www.harcourthealth.com/SIMON/KeeHayes/pharmacology/)

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